AVITI24 5D multiomics now more powerful

The next wave of innovation

Scientific discovery is never static, and neither is AVITI24. Built to change the way science happens, AVITI24 continues to expand with new capabilities that empower researchers to uncover deeper insights, ask more questions, and generate more meaningful data—all without sacrificing flexibility or performance.

AVITI24 drives discovery today and is ready to grow for tomorrow’s breakthroughs with expanded compatibility, new capabilities, and more customization options.

Product

Description

Availability

Expanded Panel Content

New Teton Immuno-Oncology and Neuroscience panels, including expanded sample type compatibility for cell suspensions and advanced segmentation algorithms for improved analysis.

Now available

Protein Customization

Understand the targets that mean the most to your research with custom protein analysis. Includes:

  • 88-plex custom add-on
  • Custom antibody screening kit
  • Teton focus panels

Now available

48-well configuration

High-throughput molecular profiling in a single run with 48-well configuration.

Now available

Teton Atlas with Direct In Sample Sequencing

Discovery and hypothesis driven read-outs in one experiment with Direct In Sample Sequencing.

  • 3’ transcriptome sequencing
  • Targeted RNA sequencing (100+ cycles)

Low output: Now available

High output: coming soon

Take a deep dive into our AVITI24 Innovation Roadmap and hear from early access users in our on-demand webinar.

What’s new on AVITI24

The latest updates introduce an integrated suite of innovations that expand the power and flexibility of the system.

Teton Atlas with Direct In Sample Sequencing (DISS)

True in situ sequencing with no library prep

With fully automated, onboard RNA sequencing inside cells, Teton Atlas introduces expanded applications on AVITI24, including CRISPR screening with simultaneous optical phenotyping.

Now available, the Teton Atlas Low Output kit enables targeted sequencing for hypothesis-driven panels, like guide RNA sequencing, and is compatible with 3-plex cell paint and custom protein detection.

Learn more about DISS


Custom Protein Detection

Focus on the proteins that matter most

Our Teton Focus Panels add flexible protein customization to 5D multiomics. Each panel includes pre-designed sets of 24 target probes across immunology, oncology, neuroscience, and cell cycle research areas. Users can mix and match up to three panels per run—or combine two panels with up to 24 custom antibodies.

cytoprofiling drug-induced liver injury with Teton focus panels

Optimization reagents

Reduce risk, save resources

Determine optimal conditions before committing to a full AVITI24 run with cell culture optimization kits. Simply plate cells, perform cell paint, assemble the flow cell, and visualize on either an AVITI24 or a microscope.

Using the antibody screening kit, screen your own primary antibodies for use in a custom antibody panel—in less than 7 hours, you can determine antibody performance in a Teton assay.

optimize your cell culture for AVITI24custom protein detection, your way


Increased sequencing output

More data, lower costs

While many genomics platforms are raising prices, adding surcharges, and gating innovations, we’re taking the opposite approach. AVITI24 now delivers up to 50% more data per sequencing run compared to AVITI™ with no change in consumables and no compromise in quality. Machine learning innovation pushes performance forward providing customers a >30% reduction in cost per gigabase.

See how AVITI24 with increased sequencing power stacks up against competitors.


Expanded Panel Content

Deeper insights into complex biology

The latest Teton Immuno-oncology and Neuroscience panels broaden what’s possible on AVITI24. With expanded compatibility for cell suspensions and advanced segmentation algorithms, you can generate high-quality data across a wider range of sample types. These panels provide:

  • Automated, onboard detection of 350 RNA transcripts, 50 proteins (including phospho-proteins), and 6 cell morphology markers with a biologically relevant and supported panel.
  • Simultaneous analysis of cell typing markers, signaling molecules, and important drivers of cell function.
  • Advanced segmentation models for high-quality data for both intracellular and surface markers.
data spotlight: AVITI24 for neurobiology

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