Rapid insights with affordable sequencing at any scale
Rewrite the future of genomics
AVITI is a benchtop sequencing instrument with reimagined core technology to deliver flexibility and affordability while setting the standard for data quality. An alternative model, AVITI LT, is a lower cost, lower throughput solution that brings innovative next-generation sequencing (NGS) to more labs.
Flexible throughput
Scale run output to suit virtually any application, without waiting or paying more.
Unprecedented quality
Leverage exceptional accuracy with ≥ 70% Q50 and ≥ 90% Q40 data (when using Cloudbreak UltraQ).
Independent flow cells
With a dual flow cell layout and individually addressable lanes, you can perform two parallel runs and operate each side independently.
Ultimate affordability
Extend your budget with industry-low sequencing costs and fixed reagent prices.
End-to-end workflows
Enjoy simple, complete workflows from library prep to analysis solutions.
Dedicated support
Rely on a smooth installation process and scientist-to-scientist converstaions.
Powered by ABC sequencing
We innovated the core components of sequencing to introduce a radically new way of generating genomics data while reducing run costs and improving performance.
- Avidite base chemistry (ABC) circularizes, copies, and rolls each strand into tightly bound polonies without the use of PCR.
- Fluorescent
avidites bind to each polony creating ultrastable complexes.
Low-binding surface chemistry makes the signal prominent for
highly-accurate detection.
- Rolling circle amplification
(RCA) avoids index hopping and other PCR-induced errors while ultratight
complexes reduce reagent consumption.
- The inherent flexibility of these methods establishes a strong foundation for continued performance and capability gains.
Always the right fit
Whether you need 2 billion reads per run or 100 million, one AVITI powers a wide range of experiments. Fully saturate two high-output flow cells to maximize your capacity or load one lane of a single low-output flow cell.
- No need to batch smaller experiments with precision pricing.
- Comprehensive sequencing kits run any read length from 2 x 75 to 2 x 300.
- Low-, medium-, and high-output kit options dial in a precise number of reads while maintaining affordability.
- Individually addressable lanes confine a library pool to one lane for project separation and maximum multiplexing.
Seamless Library Compatibility
Cloudbreak Freestyle™
Cloudbreak Freestyle sequencing kits ensure seamless integration with your current sequencing workflows. Compatible with our Elevate™ workflow and most third-party libraries, you can directly load linear libraries onto the AVITI, without manual library conversion.
Elevate Workflow
The Elevate Workflow prepares libraries from input DNA for sequencing on AVITI. Equipped with 96 unique dual indexes optimized for color balance, this native library prep solution facilitates whole-genome sequencing and is adaptable to other applications.
Adept Workflow
The Adept Workflow makes any prepared library compatible with AVITI. Designed for simplicity, this adaptation solution capitalizes on our unique combination of cost, performance, and flexibility while maintaining your favored library prep and analysis.
AVITI LT
Offering the same technology and features as AVITI, AVITI LT provides an ABC sequencing solution to suit your budget. The only difference is throughput: AVITI LT is limited to low- and medium-throughput capabilities with the flexibility to upgrade to a full-throughput AVITI with a simple software update.