AVITI24 System and Specifications

2D and 3D Sequencing Without Compromise

Element AVITI24 still dualflowcell

Simultaneously perform NGS and cytoprofiling in a single dual-sided AVITI24 run. With a first-of-its-kind onboard image processing system, AVITI24 seamlessly delivers 2D and 3D sequencing without compromising data quality. Independent run starts and ultra-fast runtimes provide unparalleled flexibility to accelerate discovery. 

Specifications

Sequencing Specifications

Read Counta

High output:

Medium output:

Low output:

1 B reads per flow cell

500 M reads per flow cell

250 M reads per flow cell

Accuracy

> 90% Q30 with 2 x 150 and 2 x 75 cycles

> 85% Q30 with 2 x 300 cycles

> 70% Q50 with Cloudbreak UltraQ™ kitsc

Inputs

Direct loading of linear libraries with Cloudbreak Freestyle™ kits

Run Timeb

≤ 24 hours 2 x 75 cycles

≤ 38 hours 2 x 150 cycles

≤ 60 hours 2 x 300 cycles

a Performance metrics are based on sequencing Element libraries. Actual results might differ due to library type and preparation methods.b Individually addressable lanes and custom recipes can extend run times.c Based on Elevate™ libraries and specific run parameters.

Cytoprofiling Specifications

Analytes

RNA, protein, morphology

100 bp in situ RNA sequencing in 2025

Plex

RNA: 350 targets

Protein: 50 targets

Morphology: 6 markers

Content

MAP Kinase Cell Cycle and Apoptosis

Immunology, neuroscience, and custom panels in 2025

Imaging

< 250 nm subcellular spatial resolution with multi-feature cell segmentation

Inputs

Adherent cells

Cell suspensions in 2025

Sensitivity

1 M mean counts detected per mm²

Throughput

Up to 1 M cells with 10 cm² area per flow cell

Two flow cells per run

Format

12 wells (0.5 cm²/well)

1 well (10 cm²/well)

Run Time

24 hoursa

Sample Prep

45 minutes

Run times based on a single 12 well run with software update available in early 2025.

System Specifications

Instrument Configuration

Dual flow cells

AVITI Operating Software

Ubuntu Core 20.04 LTS operating system

Operating Environment

Temperature: 18°C to 26°C

Elevation: < 2000 m

Sound level: ≤ 62 db at 3.3 ft

Instrument Dimensions

(H x W x D) 29.5 in x 37.6 in x 28.5 in

Weight: 155.1 kg/342 lb

Power Requirements

100–240 VAC at 50/60 Hz

15 A, 550 W (average)

Ordering Information

Element AVITI24 System

880-00004

Element AVITI24 Upgrade

895-00060

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